Since its discovery in 1928, penicillin and penicillin-related antibiotics helped save countless lives from bacterial infections. However, in the face of overuse and misuse of antibiotics, bacteria evolved resistance mechanisms that allow them to proliferate even in the presence of the newest antibiotics. Watch this video to learn how penicillin and penicillin-related antibiotics disrupt the bacterial life cycle, and what molecular mechanisms bacteria employ to evade the action of these drugs. Learn more about antibiotic resistance from PDB-101 Story by: Stephen K. Burley, David S. Goodsell, Maria Voigt Animation and Video Editing: Maria Voigt Narration: Brian Hudson
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