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This is an excerpt from a documentary covering the phenomenon known as “cluster headaches“, the pain of which is said to be worse than natural childbirth or amputation without anesthetics. In short, the worst pain known to man. The guy's name in this video is “Chuck“. He reportedly suffers from a heart condition with makes him unable to take most abortive drugs, so the only way he can attempt to stop the attacks is by breathing pure oxygen. By the looks of this video, it doesn't help much. This documentary was made by a group advocating the use of such drugs as LSD and psylocibin (found in shrooms), which have reportedly had great effect in aborting “cluster cycles“
