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Pharmacy Compounding 101 Recap: PPE Recommendations in Handling HDs as per USP 800 What are the Personal Protective Equipment (PPE) Recommendations as per USP 800? Wearing of the appropriate PPE is mandatory because it provides ✔️Worker Protection to reduce exposure to HD aerosols and residues. ✔️Product protection for sterile preparations to reduce cross-contamination. Additional PPE may be required to handle the HDs outside of a C-PEC, such as treating a patient or cleaning a spill. Appropriate PPE must be worn when handling Hazardous Drugs (HDs) during: • Receipt • Storage • Transport • Compounding (Sterile and Non-sterile) • Administration • Deactivation, decontamination, cleaning, and disinfecting • Spill control • Waste disposal What PPE should you wear when handling Hazardous Drugs? Note: PPE donning and doffing sequences depend on the Standard Operating Procedures (SOPs) of the institution and may vary
