Virology Lectures 2020 #8: Viral DNA Replication

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18 Mar 2020

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In this lecture we reveal the mechanisms of DNA replication, including how origin-binding proteins recruit the host synthetic apparatus, replication by strand displacement or a replication fork, solving the 5’-end problem caused by RNA priming, and how viral genomes ensure that cells are actively duplicating their DNA to provide access to the DNA synthesis machinery.

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