Ivermectin, is a Food and Drug Administration (FDA)-approved antiparasitic drug, Direct from official FDA site used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies. For these indications, ivermectin has been widely used and is generally well-tolerated Ivermectin is not approved by the FDA for the treatment of any viral infection. Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19 (in vitro studies) suggest that ivermectin acts by, Inhibiting host importin nuclear transport proteins Interfere with SARS-CoV-2 spike protein attachment to the human cell membrane Some studies of ivermectin have also reported potential anti-inflammatory properties Shown to inhibit replication of SARS-CoV-2 in cell cultures COVID-19 medical misinformation policy If you're posting content Don't post content on YouTube if it includes any of the following: Treatment misinformation: Content that claims that there's a guaranteed cure for COVID-19 Content that recommends use of Ivermectin or Hydroxychloroquine for the treatment of COVID-19 Categorical claims that Ivermectin is an effective treatment for COVID-19 Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19 Other content that discourages people from consulting a medical professional or seeking medical advice Prevention misinformation: Content that promotes prevention methods that contradict local health authorities or the WHO. Claims that there is a guaranteed prevention method for COVID-19 Claims that any medication or vaccination is a guaranteed prevention method for COVID-19 Content that recommends use of Ivermectin or Hydroxychloroquine for the prevention of COVID-19 Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19 Monitoring, Adverse Effects, and Drug-Drug Interactions The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans. This warning was updated and reiterated in 2021. FDA, Recommendation The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials The Panel will continue to review emerging data on ivermectin use, including the results from 2 large, ongoing randomized controlled trials. Clinical Trials Several clinical trials evaluating the use of ivermectin for the treatment of COVID-19 are currently underway or in development. Please see for the latest information. Bangkok Egypt Malaysia Is this one of the two? Ivermectin to be investigated in adults aged 18 as a possible treatment for COVID-19 in the PRINCIPLE trial 23 June 2021 Time line
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