MicroRNA Requirements in C. elegans Embryogenesis / Curr. Biol., Oct. 29, 2020 (Vol. 30, Issue 24)

MicroRNAs are critical regulators of gene expression in animal development. In C. elegans, removal of miRNAs causes developing embryos to arrest before the basic body architecture is established. Using a Microprocessor bypass strategy, we show that only two miRNAs are responsible for this phenotype, and are furthermore sufficient for morphogenesis and organogenesis in the absence of all other miRNAs. Check out the paper at (20)31436-6. P.J. Dexheimer,