On December 14, 2019, Lopez challenged the IBF lightweight champion Richard Commey. Lopez won the IBF title in spectacular fashion after connecting on Commey with a big right hand, and finishing him with a second-round technical knockout. After the conclusion of the fight, Lopez was joined in the ring by fellow lightweight champion Vasiliy Lomachenko, with whom he took a photo with. When asked about his plans for his next fight and a possible unification bout with Lomachenko, Lopez replied, “You guys know who I want,“ referring to Lomachenko without explicitly naming him
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