Mchunu made his first WBC Silver title defense against the 2016 Olympic gold medalist Evgeny Tishchenko on 27 March 2021, at the RCC Boxing Academy in Yekaterinburg, Russia, in what was the WBC cruiserweight title eliminator as well. He won the fight by unanimous decision, with scores of 117-111, 117-111 and 119-109. By beating Tishchenko, Mchunu earned the status of mandatory challenger to the reigning WBC champion Ilunga Makabu, who handed Mchunu his second professional loss
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