Evolution of GLP1 Receptor Agonists

GLP-1 receptor agonists are now used for the treatment of type 2 diabetes and obesity. Looking back, GLP-1 was found to be a cleavage product of proglucagon processing.A key breakthrough came from the discovery of is a peptide with agonistic properties at the GLP-1 receptor but resistance to degradation by , the first oral GLP-1 receptor agonist, marked the next milestone. GLP-1 New Drug R&D Service Medicilon provides GLP-1 drug discovery, CMC research (API formulation), pharmacodynamics research, PK study, GLP-1 safety evaluation and other services.