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A frameshift mutation occurs when the addition or deletion of DNA bases (except in multiples of three) changes the way the sequence is read during protein synthesis. This shift alters the reading frame of the genetic code, leading to the production of a completely different amino acid sequence downstream from the mutation. Frameshift mutations can have profound effects on the structure and function of the resulting protein, often leading to nonfunctional proteins or, in some cases, disease. They are critical in genetic research and understanding genetic disorders. The addition of a single nucleotide to the DNA sequence causes a frameshift mutation. A) True B) False In a frameshift mutation all of the amino acids before the shift are changed. A) True B) False
