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L-Arginine for the Treatment of Erectile Dysfunction Arginine is a Natural Remedy for Erectile Dysfunction (ED) -- which doctors define as the repeated inability to get or maintain an erection firm enough for sexual intercourse. High doses of L-arginine can help improve sexual function, but only in men with abnormal nitric oxide metabolism, such as that associated with cardiovascular disease, as reported in a 1999 trial published in the online journal BJU International.
