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Video of viruses assembling

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To understand how viruses assemble, researchers attached viral RNA strands to a substrate, like stems of a flower, and flowed proteins over the surface. Then, using the interferometric microscope, they watched as dark spots appeared and grew steadily darker until they were the size of full-grown viruses. By recording intensities of those growing spots, the researchers could actually determine how many proteins were attaching to each RNA strand over time.

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