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Here is a clip from a documentary outlining the role Hemophilia played in overthrowing the House of Romanov. Movies on Rasputin Healer of Alexei - Rasputin: The Mad Monk - Rasputin: Dark Prophet Books on Rasputin Healer of Alexei - Rasputin: Faith, Power, and the Twilight of the Romanovs - Rasputin: The Untold Story - A Guarded Secret: Tsar Nicholas II, Tsarina Alexandra and Tsarevich Alexei’s Hemophilia House of Romanov was the reigning royal house of Russia from 1613 to 1917. And in 1894 Nikolai II Alexandrovich Romanov became tsar, Tsar Nicholas II married his fiancée, Alix of Hesse-Darmstadt, a favorite grandchild of Queen Victoria of the United Kingdom. Alexandra was a carrier of the gene for haemophilia, inherited from her maternal grandmother, Queen Victoria. Her son, Alexei, the long-awaited heir to the throne, inherited the disease and suffered agonizing bouts of protracted bleeding, the pain of which was sometimes partially alleviated by Rasputin's ministrations. Nicholas and Alexandra also had four daughters, the Grand Duchesses Olga, Tatiana, Maria and Anastasia. Germany declared war on Russia on August 1, 1914 and its ally France on August 3, 1914, which started the First World War. The aristocracy was alarmed at the powerful influence of the peasant priest Rasputin over the tsar. The severe military losses led to a collapse of morale at the front and at home, leading to the fall of the House of Romanov in the February Revolution of 1917. Nicholas abdicated on behalf of himself and his son. He was imprisoned with his family by the Bolsheviks and executed in July 1918.
