CELL-TO-CELL COMMUNICATION Oral Health and Systemic Health

CELL-TO-CELL COMMUNICATION – ORAL HEALTH AND SYSTEMIC HEALTH: THE INTERLINK BETWEEN PERIODONTITIS AND DIABETES Supported by SUNSTAR Produced by Quintessence International Publishing Group| iAS interActive Systems Authors: S. Jepsen, M. Sanz, B. Stadlinger, H. Terheyden Advisory Board: I. Chapple, R. Genco, E. Lalla, S. Murakami This is the version for consumers. A spectacular 3D film on the links between periodontitis and diabetes This 3D animated film, supported by SUNSTAR and produced by the Quintessence International Publishing Group, illustrates how periodontitis and other inflammatory processes of the oral cavity may contribute to systemic conditions such as atherosclerosis or diabetes, or negatively influence their course. Oral Health and Systemic Health addresses its subject by using innovative 3D animations to visualize some of the key aspects of the molecular and cellular links between periodontal infection/inflammation and systemic diseases/conditions such as atherosclerosis and type 2 diabetes. Main scientific topics covered: ・Dissemination of periodontal bacteria into the circulation, thereby eliciting systemic inflammation that may lead to: 1. Promotion of atherosclerosis, and 2. Impaired glycemic control, with negative effects on the periodontium. ・Potential benefits of periodontal treatment. Specialist input was provided by an international team of experts including the authors Prof. Søren Jepsen (Germany), Prof. Mariano Sanz (Spain), Dr. Bernd Stadlinger (Switzerland) and Prof. Hendrik Terheyden (Germany), as well as an advisory board whose members were Prof. Iain Chapple (UK), Prof. Robert Genco (USA), Prof. Evanthia Lalla (USA), and Prof. Shinya Murakami (Japan).