Guest
This is the first installment of a series dedicated to the molecular biology of unusual types of cancers called hyperprogressive disease that are colloquially referred to as “turbo cancers” (not a term used in medicine). In this episode, we provide the first ever published evidence of how IgG4 antibodies can play a role (in conjunction with other molecular events) in the development of turbo cancers. What we cover: *Turbo cancers exist in medicine but are called hyperprogressive disease *Turbo cancers appear to require 3 elements in the same environment: *cancer presence, *high IgG4 levels and *high glutathione levels *IgG4 immune checkpoint inhibitors used in cancer treatment *Hyperprogressive disease (turbo cancers) first described after the use of immune checkpoint inhibitors that were IgG4 *Molecular understanding of how it happens only emerged in the last 5 years *Turbo cancers are still emerging knowledge as only a handful science papers published *2019 study of turbo cancer patients shows unique immune cell behaviour in cancers *2019 study of turbo cancers in mice provide genetic background predisposition Location: Calgary, Alberta Described content: __________________________________________________________________ Dr. Raszek Credentials: ____________________________________________________________________ Please stay in touch with us on other social media channels: Twitter: Facebook: Blog: Previously Microsoft was providing inappropriate warning about our newsletter sign up. If this happens again, there is an alternative option. Original Newsletter sign up (safe!): Alternate Newsletter sign up: Instagram: Patreon:
