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The Multiple Faces of SDHB-Related Paraganglioma

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Dr. Ali Alzahrani, King Faisal Hospital and Research Centre, Riyadh, Saudi Arabia, joins us to talk about SDHB mutations and their different expressions among those with pheochromocytoma and paraganglioma. Part of the Pheo Para Alliance Education Webinar Series. Questions and timing are as follows: Q 1 at 48:16 Are there subtypes of SDHB? Q 2 at 49:16 Is it common to be the only SDHB-positive person in your immediate family? Q 3 at 50:59 Is it common to be the first person in your family with the SDHB mutation? Q 4 at 52:39 If you have SDHB, but no expression of the gene (all mri’s are clean, all blood work good) and has been for over 10 years, how important is it to continue surveillance? Q 5 at 54:26 We've seen renal cell carcinoma, glomus jugulare and GIST in my SDHB family. Are there others to worry about? Q 6 at 57:03 Is there a diet that's most appropriate for SDHB carriers —with history of tumor or for those who don’t have news of tumors yet? Is diabetes common with SDHB?

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