How to apply Chargaff's rule

Chargaff's rules state that DNA from any species of any organism should have a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A G=T C) and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine. This pattern is found in both strands of the DNA. They were discovered by Austrian-born chemist Erwin Chargaff, in the late 1940s. #charGaffsRule #DNA #mRNA #RNA #nucleotide #basePair #ChargaffsRule #genetics #dnaReplication #chargaffsRuleOfDna #chargaffsRuleProblems #watsonAndCrick #chargaffsRuleExplained #dnaBasesPairing #complementaryBasePairing #DNASequence #dnaComplementarySequence #dnaSequenceComplementaryStrand #Guanine #Cytosine #Adenine #andThymine #dnaSemiConservativeReplication #replicationFork #dnaReplicationSong #dnaTranscription #initiation #elongation #termination