Nobel Prize 2022: Organic Chemistry - Click Chemistry: Retrosynthetic analysis of this small molecule chromophore, a dye with push-pull functionality across its conjugated pi system. (CORRECTION: at 16:45, bottom-left corner of screen - the reagent should be NaOH, not LiAlH4) Discussion inspired by this reference: Eur. J. Org. , 5591 Click Chemistry is also known as Bio-Orthogonal Chemistry. This type of Chemistry won the Nobel Prize in 2022 for Bertozzi, Meldel and Sharpless. This molecule is typical of a small molecule chromophore that could be investigated as part of a library of organic compounds in the development of organic electronics. For example, in organic light-emitting diodes (OLEDs) or organic solar cells (photovoltaics, OPVs). The push-pull arrangements of hetereocycles at the ends of this molecules will lead to molecular orbitals that are spatially distinct - with big differences in space for the bonding and antibondi
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