I absolutely do not condone the usage of this “Drug“, It is an absolutely egregious experience and i'm not just reffering to the “high“ which is by definition classified as a toxidrome in various medical literature. I wholeheartedly believe that this drug is leagues worse than heroin in terms of the long term effects it imposes onto its users, I'm speaking symptoms of early-onset Dementia and cardiovascular issues that give young people the heart of a 50 year old. I firsthand have spoken to people who have absolutely wrecked their mind through heavy usage of this “drug“, Although these effects are not limited to heavy usage (Long-term therapeutic use does tend to cause some issues). I've seen people go from normal functioning adults to severely impaired because they abused this shitty allergy medication. Trust me, although the majority of the DEA drug propaganda is bullshit they got one fucking thing right, there does exist a fucking drug so terrible it turns you into a complete shell of yourself all the while you witniss what's most beloved to you dissipate, however they didn't have the foresight to realize it's being sold over the goddamn counter. I will now go over a list of various symptoms experienced by people who are completely sober who have used this drug more than twice. Keep in mind the severity of these symptoms are unpredictable and not at all consistent, Some people will experience some of these symptoms, Others will experience a good chunk of these symptoms, and some may not experience any of this however the majority do report atleast one of these symptoms after cessation of use. Mental symptoms: Terrible short term memory, The inability to comprehend simple problems, Heavy DP/DR, re-experiencing of hallucinations (Not hppd, Literal delerium while sober), HPPD (Which has its own array of symptoms that I will not go over here), Difficulties with verbal communication, Emotional disregulation, Downregulated dopamine receptors (In essence, this means you will experience less joy and fullfillment from tasks you would normally experience joy and fullfillment from) (Not proven but this has been reported multiple times in frequent users of dph) , Lower than average levels of acetylcholine (A neurotransmitter implicated in Memory, Learning, Eye accomodation)(Not proven, Hypothetical as I believe there is no actual method to measure acetylcholine levels in humans. However this is an anticholinergic so it's safe to assume it does change areas of the brain responsible for acetylcholine regulation), Drop in IQ, Time dilation, Decrease in reading comprehension and speed, Constant tiredness, Loss of music appreciation, Increased Sensitivity to histamine, Reduction in gray matter volume and various other changes in neurochemistry. Physical symptoms: Urine retention, Muscle tissue loss (Including the heart), Damage to the cardiovascular system, Drymouth, Weight loss, Paleness of the skin, Dehydration, High heartrate, Damage to the kidneys. Reddit posts which speak about the damage induced by this drug: Actual scholarly articles: (The use of a scopolamine model to study the potential nootropic effects of aniracetam and piracetam in healthy volunteers) (This is relevent because they use a potent anticholinergic that's very similiar in mechanism to diphenhydramine to simulate symptoms of dementia) (Dose-dependent toxicity of diphenhydramine overdose) (Documentation of diphenhydramine toxicity by presenting statistics from hospital admissions related to a diphenhydramine overdoses) (Cognitive and Other Adverse Effects of Diphenhydramine Use in Hospitalized Older Patients) (Antihistamines, a possible risk factor for alzheimer's disease) My reasoning for some of this phenomenom: I do believe acetylcholine levels are somewhat effected after cessation of abusing this drug because alot of people report blurred vision after using this drug and acetylcholine is involved in the process of eye accommodation.
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