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Relative Risk Reduction | Dichotomous vs. Ordinal variables

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Relative Risk Reduction (RRR) is a measure used in epidemiology and clinical research to compare the risk of a certain event (such as disease, injury, or complication) between two groups: one exposed to an intervention (treatment or preventive measure) and the other not exposed (usually receiving a placebo or standard care). RRR quantifies how much the risk is reduced in the intervention group compared to the control group. Problems: Which of the following is/are ordinal data? A) NYHA I-IV B) Sex C) Improvement Yes/No D) Grade of breast cancer E) Alive or Dead In the US Nurses’ Health Study (NHS) cohort study, where they looked at association of regular aspirin use (≥two 325 mg tablets/week) and colorectal cancer in 82,911 women found (RR, ; 95% CI, –) over 20 years of follow-up. What does this say about the mortality from colorectal cancer? A) Those who takes aspirin ≥2 times/week have 23% lower risk of colorectal cancer * B) Those who takes aspirin ≥2 times/week have % lower risk of colorectal cancer C) Those who takes aspirin ≥2 times/week have 77% lower risk of colorectal cancer D) Those who takes aspirin ≥2 times/week have % reduction in death from colorectal cancer E) None of the above is correct

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